You'll see your doctor for follow-up exams and X-rays. Use of hydroxychloroquine sulfate in patients with psoriasis may precipitate a severe attack of psoriasis. When used in patients with porphyria the condition may be exacerbated. The preparation should not be used in these conditions unless in the judgment of the physician the benefit to the patient outweighs the possible hazard. Hydroxychloroquine works best when you take it on a regular schedule. For example, if you are to take it once a week to prevent malaria, it is best to take it on the same day each week. Or if you are to take 2 doses a day, 1 dose may be taken with breakfast and the other with the evening meal. Make sure that you do not miss any doses. If you have any questions about this, check with your health care professional. ipratropium
If your symptoms do not get better after several months or if they get worse, check with your doctor. If cardiotoxicity is suspected, prompt discontinuation of hydroxychloroquine sulfate may prevent life-threatening complications. Meats, poultry, fish, eggs, dried beans and peas, and tofu. Respiratory support and shock management should be instituted as necessary.
Check with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after long-term treatment. Your doctor may want you to have your eyes checked by an ophthalmologist eye doctor. Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; bizarre behavior; change in color of the skin or inside of the mouth; chest pain; difficulty seeing or reading words, letters, or parts of objects missing when reading; fever or sore throat; hair loss; hearing loss; mental or mood changes; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; sensitivity to sunlight; symptoms of liver problems eg, yellowing of the skin or eyes, dark urine, pale stools, persistent nausea or stomach pain; unusual bleeding or bruising; unusual weakness; vision problems eg, blurred vision, trouble focusing; weight loss.
If this product is used too frequently, it may cause loss of normal bowel function and an inability to have a without using the product dependence. Malaria is spread by mosquitoes. Wear long-sleeved shirts or blouses and long trousers to protect your arms and legs, especially from dusk through dawn when mosquitoes are out.
Human pregnancies resulting in live births have been reported in the literature and no increase in the rate of birth defects has been demonstrated. Embryonic deaths and malformations of anophthalmia and microphthalmia in the offspring have been reported when pregnant rats received large doses of chloroquine. The precise mechanism by which hydroxychloroquine exhibits activity against Plasmodium is not known. Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA. But hydroxychloroquine is not used alone for severe cases of lupus in which the or other organs are involved. SEE AN EYE SURGEON TWICE A YEAR to assess the retina. Hydroxychloroquine is to be used only by the patient for whom it is prescribed. Do not share it with other people. Now down to 400mg daily. Gastro problems not so severe now. My SLE symptoms were minor Sjogren's symptoms primarily and Prednisone actually solved it after a month. Dose is based on body weight and must be determined by your doctor. Plaquenil with great relief over 10 years. Apply mosquito repellent to uncovered areas of the skin from dusk through dawn when mosquitoes are out.
Use hydroxychloroquine as directed by your doctor. Check the label on the medicine for exact dosing instructions. What treatment for osteoarthritis is available? The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. Microbiology . Hydroxychloroquine sulfate tablets are not recommended for the treatment of malaria acquired in geographic areas where chloroquine resistance occurs or when the Plasmodium species has not been identified. When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well. It is not known whether this drug passes into milk. Consult your doctor before -feeding. Joint replacement or other surgical procedures are sometimes considered the “treatment of last resort” for people with osteoarthritis. Doctors frequently tell patients to wait as long as possible before joint replacement, but to get the best results, it should also not be delayed too long. What are the side effects of hydroxychloroquine? Lupus medications work in different ways. What they have in common is that they all reduce swelling in the body, Fitzgerald says. Which drugs you need -- either alone or in combination -- depends on your particular case. Combined use of methotrexate with hydroxychloroquine sulfate has not been studied and may increase the incidence of adverse effects. Hemoglobin is a main part of red and binds oxygen. If you have too few or abnormal red blood cells, or your hemoglobin is abnormal or low, the cells in your body will not get enough oxygen. -- like -- occur because organs aren't getting what they need to function properly. Keep this medicine out of the reach of children. Children are especially sensitive to the effects of hydroxychloroquine and overdose is especially dangerous in children. Taking as few as 3 or 4 tablets 250-mg strength of chloroquine has resulted in death in small children. Hydroxychloroquine is probably just as dangerous. Fitzgerald. As you get better, your will probably reduce the dose. Some people need long-term treatment with low-dose steroids; others can stop taking them altogether. This drug should be taken with a meal or a glass of milk. This medication is also used, usually with other medications, to treat certain auto-immune diseases lupus, rheumatoid arthritis when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs DMARDs. Reference Listed Drug RLD is an approved drug product to which new generic versions are compared to show that they are bioequivalent. A drug company seeking approval to market a generic equivalent must refer to the Reference Listed Drug in its Abbreviated New Drug Application ANDA. By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart. varenicline
Gently cleanse the treated area using lukewarm water and a mild soap. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. What is rheumatoid arthritis RA? Pace yourself, and plan frequent rest periods. Radiation passes through your skin, which can become red, swollen, warm, and sensitive -- as if you had a sunburn. It may peel or become moist and tender. Depending on the dose, you may lose hair or sweat less where you've been treated. As hydroxychloroquine sulfate may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or antidiabetic drugs may be required. Postmarketing cases of life-threatening and fatal cardiomyopathy have been reported with use of hydroxychloroquine sulfate as well as with use of chloroquine. Patients may present with atrioventricular block, pulmonary hypertension, sick sinus syndrome or with cardiac complications. ECG findings may include atrioventricular, right or left bundle branch block. Signs or symptoms of cardiac compromise have appeared during acute and chronic treatment. Clinical monitoring for signs and symptoms of cardiomyopathy is advised, including use of appropriate diagnostic tools such as ECG to monitor patients for cardiomyopathy during hydroxychloroquine sulfate therapy. During treatment, your doctor may occasionally recommend stopping the medication for a short time to see whether there are any changes in your behavior and whether the medication is still needed. The normal frequency of varies from once daily to 1 to 2 times weekly. Constipation is best treated by drinking plenty of fluids four to six 8-ounce glasses daily eating foods high in fiber, and regularly. Consult WARNINGS section for additional precautions. Hydroxychloroquine should not be used for a long period of time in CHILDREN; safety and effectiveness in children have not been confirmed. order generic zantac online overnight zantac
Side effects may require reduction in the initial dose for 5 to 10 days; the dose may then gradually be increased to the optimum response level. There are several types of osteoarthritis medicines. This overview offers quick, easy explanations of what they are and how they treat arthritis. Barbie SuperFedMOM. Imagine trying to mend the body of this "invincible ego nut". The doctor had to call my husband to make me take a week off to rest. i love the excitement of my job- the stress- the rush. I work crazy hours. Not good for the body, soul, or family. When I am home all I do is crash and sleep- can't move. Now- I am on the strongest medication. Therefore, -feeding is not recommended while using this drug. Consult your doctor before breast-feeding. Common treatment methods don't change the progression of osteoarthritis. However, two nutritional supplements -- glucosamine and chondroitin sulfates -- are being studied to determine if they can relieve pain or perhaps slow the breakdown of cartilage, which is a significant part of osteoarthritis. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Antacids and kaolin can reduce absorption of chloroquine; an interval of at least 4 hours between intake of these agents and chloroquine should be observed. Vertigo, tinnitus, nystagmus, nerve deafness, deafness. Are there support groups for people with rheumatoid arthritis? Disturbance of with symptoms of blurred vision. It is recommended that hydroxychloroquine be discontinued if ocular toxicity is suspected and the patient should be closely observed given that retinal changes and visual disturbances may progress even after cessation of therapy. Motta M, Tincani A, Faden D et al. Follow-up of infants exposed to hydroxychloroquine given to mothers during pregnancy and lactation. J Perinatol. Ventricular arrhythmias and torsade de pointes have been reported in patients taking hydroxychloroquine sulfate see OVERDOSAGE and DRUG INTERACTIONS. Store at room temperature up to 86 degrees F 30 degrees C away from moisture and light. Do not store in the bathroom. Children are very sensitive to the effects of this medication. It is important to keep this and all medications out of the reach of children and pets. cheapest atopica buy store
Rabies vaccine because its effectiveness may be decreased by hydroxychloroquine. Getting a shot of corticosteroids directly into a sore joint can reduce pain and inflammation quickly and effectively. This effect usually results in a within 15 to 60 minutes. Your doctor may want you to start taking this medicine 1 to 2 weeks before you travel to an area where there is a chance of getting malaria. This will help you to see how you react to the medicine. Also, it will allow time for your doctor to change to another medicine if you have a reaction to this medicine. Red blood cells can be lost through bleeding, which often can occur slowly over a long period of time, and can go undetected. Keep out of the reach of children. Long-term studies in animals have not been conducted to evaluate the carcinogenic potential of hydroxychloroquine sulfate. Rest. People with lupus might need more rest than the average person. If you can, build time for rest into the day and allow for 8 to 10 hours of a night. This product is not recommended for use in children younger than 6 years unless directed by a doctor. Read the Guide provided by your before you start taking and each time you get a refill. If you have any questions, ask your doctor or pharmacist. whol.info cycrin
Dr's advice Bioten, it didn't help much. Anyhow, in 2008 I continued the use 400 mgs plaqenil and no Ibuprofen was need-felt awesome. Late 2008, I have noticed itchy skin even in my vaginal area -Derms say dry skin. Dr's permission reduce to 200mgs and so far so good and still no Ibuprofen needed. Derm said take zyrtec durning day benadryl at night -works! Americans. Women, young children, and people with chronic diseases are at increased risk of anemia. Children are especially sensitive to the effects of hydroxychloroquine. This may increase the chance of side effects during treatment. Overdose is especially dangerous in children. NF. Keep out of the reach of children. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs including any herbal medicines or supplements or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors. Brachytherapy can be used alone or with external beam radiation. Products meeting necessary bioequivalence requirements. Hydroxychloroquine sulfate tablets do not prevent relapses of P. vivax or P. ovale because it is not active against the hypnozoite forms of these parasites. Take this medication with or without food as directed by your doctor, usually once daily in the morning.
Lupus is mainly treated with medicine. Safety and efficacy have not been established in the chronic use of hydroxychloroquine sulfate for systemic lupus erythematosus and juvenile idiopathic arthritis in children. Children are especially sensitive to the 4-aminoquinoline compounds. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. International experts indicate that hydroxychloroquine is acceptable during breastfeeding. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication. If your symptoms do not improve within a few days or a few weeks or months for arthritis or if they become worse, check with your doctor. Skeletal muscle myopathy or neuropathy leading to progressive weakness and atrophy of proximal muscle groups, depressed tendon reflexes, and abnormal nerve conduction, have been reported. Muscle and nerve biopsies have been associated with curvilinear bodies and muscle fiber atrophy with vacuolar changes. Assess muscle strength and deep tendon reflexes periodically in patients on long-term therapy with hydroxychloroquine sulfate. Milk, cheese, and yogurt. Hydroxychloroquine sulfate tablets are indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. If you are thinking about hip or knee replacement surgery, here are 10 important questions to ask your doctor. Patients must have health insurance and their insurance must cover the qualifying medication for which they seek assistance. Corneal changes including edema and opacities can be symptomless or may cause disturbances such as haloes, blurring of vision or photophobia. They may be transient and are reversible when therapy is discontinued. An increased plasma cyclosporin level was reported when cyclosporin and hydroxychloroquine sulfate were coadministered. RxList is part of the WebMD Health Network. The opinions expressed in the WebMD User Reviews are solely those of the User, who may or may not have medical or scientific training, and do not represent the opinions of WebMD. These member reviews have not been reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other purpose except for compliance with our Terms and Conditions. pyrantel buy online shopping usa
The molecular weight of hydroxychloroquine sulfate is 433. Do not use medications containing amphetamine or dextroamphetamine while using lisdexamfetamine. Doing so may cause the product to be less effective. Lie on your left side with the right slightly bent. Gently insert the suppository, pointed end first, toward the navel and well up into the rectum. Several months of therapy may be required before maximum effects can be obtained. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs. NO SYMPTOMS of eye problems until the eye went completely blind OVERNIGHT. If you ARE on this medication. Following chronic oral administration of hydroxychloroquine, significant levels of three metabolites, desethylhydroxychloroquine DHCQ desethylchloroquine DCQ and bidesethylhydroxychloroquine BDCQ have been found in plasma and blood, with DHCQ being the major metabolite. The absorption half-life was approximately 3 to 4 hours and the terminal half-life ranged from 40 to 50 days. The long half-life can be attributed to extensive tissue uptake rather than through decreased excretion. Peak plasma levels of hydroxychloroquine were seen in about 3 to 4 hours. Renal clearance in rheumatoid arthritis RA patients taking hydroxychloroquine sulfate for at least six months seemed to be similar to that of the single dose studies in volunteers, suggesting that no change occurs with chronic dosing. Range for renal clearance of unchanged drug was approximately 16 to 30% and did not correlate with creatinine clearance; therefore, a dosage adjustment is not required for patients with renal impairment. Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria chloroquine-resistant. The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Fitzgerald. "A drug might work well in some people and not at all in others. Unfortunately we don't have a way to predict who will benefit and who won't. Hydroxychloroquine is usually available as the sulfate salt with hydroxychloroquine constituting about 75% of the labeled dose of hydroxychloroquine sulfate. It has a half-life of over a month. Some studies have not been clear about the salt form and dosage of the products being taken and others have sampled milk after only a few doses before steady state was reached. These flaws make interpretation of some of the data difficult. Remember that your doctor has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this not have serious side effects. Your doctor can answer questions about side effects, the goals of your treatment, and how the cancer is responding to radiation. Urine hydroxychloroquine levels were still detectable after 3 months with approximately 10% of the dose excreted as the parent drug. Patients should be strongly warned to keep these drugs out of the reach of children see OVERDOSAGE. Do not take that may increase bruising, particularly if you take a blood-thinning medicine. order now zanaflex payment otc
Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. BUT, I AM NOT EVEN CLOSE to being a doctor, AND I don't know how severe your Lupus is. But when my doc let me try I didn't have a weaning process I was on 200mg am and 200 pm. I'd rather see you get a second opinion, but I'm telling you what I know because we all do what we want to do in the end. Rash, pruritus, pigmentation disorders in skin and mucous membranes, hair color changes, alopecia. Dermatitis bullous eruptions including erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms DRESS syndrome photosensitivity, dermatitis exfoliative, acute generalized exanthematous pustulosis AGEP. AGEP has to be distinguished from psoriasis, although hydroxychloroquine sulfate may precipitate attacks of psoriasis. It may be associated with pyrexia and hyperleukocytosis. WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider. If objective improvement such as reduced joint swelling, increased mobility does not occur within 6 months, therapy should be discontinued. What are complications of rheumatoid arthritis? It is very important that you take this medicine only as directed. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of serious side effects. Some people taking this medication over long periods of time or at high doses have developed irreversible damage to the retina of the eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Plaquenil is also used to treat symptoms of and discoid or systemic erythematosus. Plaquenil is available in generic form. Other medications. Because lupus can affect so many different parts of the body, many people need other medications depending on their symptoms. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. What research is being done on rheumatoid arthritis? Hydroxychloroquine sulfate prolongs the QT interval and should not be administered with other drugs that have the potential to induce cardiac arrhythmias. Also, there may be an increased risk of inducing ventricular arrhythmias if hydroxychloroquine sulfate is used concomitantly with other arrhythmogenic drugs. cyproheptadine in canada walmart
This product should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: intestinal blockage obstruction. Symptoms may include blurred vision; excessive excitability; fainting; headache; irregular heartbeat; loss of consciousness; mood changes; seizures; severe drowsiness or dizziness; slow, shallow breathing. SLE -- might not have a cure, but it's a highly treatable condition. Lupus can help lower long-term risks and keep symptoms under control. According to the Lupus Foundation of America, 80% to 90% of people with lupus can expect a normal lifespan with good treatment. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. To treat lupus erythematosus, the average adult dose is 400 mg once or twice daily. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. You can talk to a hospital social worker about your feelings, family concerns, financial issues, and other aspects of your personal situation. What tests do physicians use to diagnose rheumatoid arthritis? Find out what happens during hip replacement surgery and what to expect afterwards. COMPLETELY BLIND. Eye surgeon diagnosed RUPTURED RETINA. If you are taking this medicine to help keep you from getting malaria, keep taking it for the full time of treatment. If you already have malaria, you should still keep taking this medicine for the full time of treatment even if you begin to feel better after a few days. This will help to clear up your infection completely. If you stop taking this medicine too soon, your symptoms may return. lamisil
It appears that the 8 infants reported in the letter were included among the 13 infants in the case series, but it is unclear whether the 16 infants reported in the abstract were part of the case series. Peak blood concentrations of metabolites were observed at the same time as peak levels of hydroxychloroquine. It took a long time for me to receive the correct diagnosis. I had to tell myself that it would take my body sometime to adjust to the medication. The Lupus was permitted to wreak havoc - it was a long battle for the plaquenil to fight. Rarely scotomatous vision or field defects may occur without obvious retinal change. Disclaimer: The indications, uses and warnings for individual medications outside the USA are determined by local regulatory bodies in each country or region. The Drugs. Thirteen women who were on long-term hydroxychloroquine donated milk samples at 7 time points between 0 and 18 hours after a dose. Nation RL, Hackett LP, Dusci LJ et al. Excretion of hydroxychloroquine in human milk. Br J Clin Pharmacol.
This medication may be swallowed whole. However, if you have trouble swallowing the medication, you may open the capsule and pour all of its contents powder in a glass of water or orange juice or mix it in yogurt. Use a spoon to break apart any powder that is stuck together. Stir well until the contents dissolve completely. Drink or eat the mixture right away. Do not prepare a supply in advance. It is normal to see a filmy coating on the inside of your glass or container after you drink or eat all of the medicine. What is the treatment for rheumatoid arthritis? Hydroxychloroquine is active against the erythrocytic forms of chloroquine sensitive strains of Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, and Plasmodium vivax. Hydroxychloroquine is not active against the gametocytes and exoerythrocytic forms including the hypnozoite stage P. vivax and P. ovale of the Plasmodium parasites. If you miss a dose, take it as soon as you remember in the morning hours. If it is afternoon or near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Contact your health care provider if you notice any muscle weakness or problems with your vision or hearing. Your knee and ankle reflexes will be tested periodically. Treatment for osteoarthritis comes in many forms -- from exercise to surgery. Learn more about your options here. Chloroquine has been reported to reduce the bioavailability of praziquantel. Benlysta. Benlysta was approved in 2011 to treat lupus in combination with other lupus drugs. Although it does not benefit all patients with lupus, it helps some reduce doses of steroids, which can have troubling side effects. Benlysta, also called belimumab, is an antibody that recognizes and blocks a protein in the immune system that contributes to the immune system's attack on the body's own cells. cheap valacyclovir 10 mg
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Safe use of this drug in the treatment of juvenile rheumatoid arthritis has not been established. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Find out who needs it and what to expect. Take hydroxychloroquine sulfate with a meal or a glass of milk. None had evidence of retinal, motor or growth abnormalities during 12 months of follow-up. The authors conclude that the benefits of breastfeeding outweigh the risk of hydroxychloroquine.
Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior . This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction. Do not increase your dose or use this drug more often or for longer than prescribed. Properly stop this medication when so directed. It's important to hold still and stay relaxed. Cameras and an intercom allow the therapist to see and hear you. Tell her right away if you're concerned about something. Infant Levels. Relevant published information was not found as of the revision date.
Diarrhea; dizziness; loss of appetite; mild headache; nausea; stomach cramps. Suppressive therapy should begin 2 weeks prior to exposure; however, failing this, an initial dose of 800 mg 620 mg base may be taken in 2 divided doses 6 hours apart. Once you start feeling well- start to do light exercises.
Rare but potentially serious eye toxicity can occur. What about rheumatoid arthritis and pregnancy? Hydroxychloroquine sulfate should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. This medication may rarely cause serious sometimes permanent eye problems or muscle damage, especially if you take it for a long time.